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Methylamine is an effective nucleophile as it is an unhindered amine.[fourteen] As an amine it is considered a weak foundation. Its use in organic chemistry is pervasive. Some reactions involving very simple reagents involve: with phosgene to methyl isocyanate, with carbon disulfide and sodium hydroxide into the sodium methyldithiocarbamate, with chloroform and base to methyl isocyanide and with ethylene oxide to methylethanolamines. Liquid methylamine has solvent Qualities analogous to those of liquid ammonia.[fifteen]

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